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Alias names |
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SNCA; NACP; PARK1; alpha-Synuclein; Synuclein alpha
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Concentration |
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1 mg/ml (determined by Bradford assay)
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Substrate/Buffer |
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Liquid. In 20mM Tris-HCl buffer (pH 7.5) containing, 10% glycerol
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Storage |
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Can be stored at +4°C short term (1-2 week). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles
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References |
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Ueda K., et al. (1993) Proc. Natl. Acad. Sci. USA 90:11282-11286
Kim J., et al. (1997) Molecules and Cells 7:78-83
Jakes R., et al. (1994) FEBS lett. 345:27-32
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Notes |
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Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140 amino acids, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. Recombinant mouse alpha-Synuclein, was expressed in E.coli and purified by using conventional chromatography techniques
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